Status:

UNKNOWN

90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment

Lead Sponsor:

General Hospital of Ningxia Medical University

Conditions:

Adverse Effect

Eligibility:

FEMALE

18-45 years

Phase:

NA

Brief Summary

The objective of this study is to investigate the 90% effective dose of phenylephrine infusions for preventing postspinal anesthesia hypotension under intensive and standard treatment during cesarean ...

Detailed Description

Post-spinal anesthesia hypotension is a frequent complication during spinal anesthesia for cesarean section. The incidence of post-spinal anesthesia hypotension is as high as 62.1-89.7% if prophylacti...

Eligibility Criteria

Inclusion

  • 18-45 years
  • Primipara or multipara
  • Singleton pregnancy ≥37 weeks
  • American Society of Anesthesiologists physical status classification I to II
  • Scheduled for cesarean section under spinal anesthesia

Exclusion

  • Body height \< 150 cm
  • Body weight \> 100 kg or body mass index (BMI) ≥ 40 kg/m2
  • Eclampsia or chronic hypertension or baseline blood pressure ≥180 mmHg
  • Hemoglobin \< 7g/dl

Key Trial Info

Start Date :

April 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2025

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06151522

Start Date

April 1 2025

End Date

June 30 2025

Last Update

November 30 2023

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