Status:
RECRUITING
A New Neuroregulatory Technology for the Therapy of AN Based on the Pathological Neural Network of ACC
Lead Sponsor:
Shanghai Mental Health Center
Collaborating Sponsors:
Shanghai Tongji Hospital, Tongji University School of Medicine
Huadong Hospital
Conditions:
Feeding and Eating Disorders
Eligibility:
FEMALE
18-35 years
Phase:
NA
Brief Summary
Hypothesis of "AN-ACC pathological network" suggests that ACC overactivation and abnormal functional connectivity with other brain regions is the neuropathological mechanism for the onset of AN. Curre...
Detailed Description
Building on the previous foundation and literature review, we found that ACC is closely related to the core symptoms of AN, and proposed the hypothesis of "AN-ACC pathological network", suggesting tha...
Eligibility Criteria
Inclusion
- Female, aged 18-35 years, right handedness.
- Above primary education.
- Meet the diagnostic criteria of AN in DSM-V, and13.0 kg/m2 ≤ body mass index (BMI)\<18.5 kg/m2.
- No systemic nutritional therapy, psychiatric medication or any form of psychotherapy have been received within 1 month before enrollment.
- Able to understand the nature of this study and sign an informed consent form.
Exclusion
- Diagnosed with a DSM-5 disease other than anorexia nervosa, or at high risk of suicide, strong impulsive behavior as well as anti-social behavior.
- With severe physical or cognitive impairment.
- Not able to undergo MRI.
- Considered unsuitable for enrollment in this clinical trial for other reasons.
Key Trial Info
Start Date :
April 30 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06152640
Start Date
April 30 2024
End Date
May 31 2026
Last Update
April 26 2024
Active Locations (1)
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1
Jue Chen
Shanghai, Shanghai Municipality, China, 200030