Status:
UNKNOWN
Role of the Nasal Environment in Obesity
Lead Sponsor:
Katharina Timper
Conditions:
Adiposity
Eligibility:
All Genders
18-55 years
Brief Summary
The primary aim of this study is to investigate the nasal environment in obese and lean individuals.
Eligibility Criteria
Inclusion
- N=50 adult male and female patients with obesity will be included in this study.
- Inclusion criteria:
- Inclusion criteria:
- Age 18-55 years
- Written informed consent
- BMI \> 30 kg/m2
- N=50 adult lean patients age- and sex-matched to the group of obese patients will be included in this study.
- Inclusion criteria:
- Age 18-55 years
- Written informed consent
- BMI 18-25 kg/m2
- N=50 adult male and female patients with obesity with scheduled bariatric will be included in this study
- Inclusion criteria:
- Age 18-55 years
- Written informed consent
- BMI \> 35 kg/m2
Exclusion
- Smoking
- Chronic or acute sinusitis
- Surgical intervention of the nasal cavity or the paranasal sinus
- Use of antibiotics within the last 31 days18
- Current illicit drug abuse including daily marijuana or CBD consumption (≤ 24 g of alcohol per day allowed)
- Any kind of severe chronic disease (e.g. severe heart failure, active cancer disease)
- Use of any kind of decongestant more than twice a week
- Use of cortisone-containing nasal spray within the last 3 months
- Acute allergic rhinitis
- History of neurodegenerative diseases
- History of severe head trauma
- Severe renal impairment (e.g. estimated glomerular filtration rate \<30 ml/min/m2)
Key Trial Info
Start Date :
July 30 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2025
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT06153654
Start Date
July 30 2021
End Date
September 1 2025
Last Update
December 1 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital Basel
Basel, Switzerland