Status:
UNKNOWN
The Effects of a 12-week Combined Exercise Intervention on the Gut Microbiome of Older Adults
Lead Sponsor:
Nottingham Trent University
Collaborating Sponsors:
University of Reading
Conditions:
Physical Inactivity
Eligibility:
All Genders
65-85 years
Phase:
NA
Brief Summary
There are trillions of microorganisms living alongside us in our guts. Recent research has shown that this community, known as the gut microbiome, has a big influence on our health and wellbeing. Imba...
Detailed Description
The gastrointestinal (GI) tract, as well as the microbes that live and thrive there, were once thought to be just part of an organ whose only function was food digestion. However, during the last deca...
Eligibility Criteria
Inclusion
- Aged between 65-85 years old
- Healthy, free-living individuals
- Vaccinated against COVID-19
- Physically inactive (\<150 mins/week of PA)
- No participation in any exercise intervention studies in the last 3 months
- BMI Between 20-35 kg/m2
Exclusion
- The use of antibiotics 3 months before or during the study
- Cancer
- Intestinal inflammatory conditions (e.g., Crohns, ulcerative colitis)
- Consumption of proton pump inhibitors (e.g., omeprazole, lansoprazole, etc…)
- Auto-immune diseases
- GI diseases (e.g., IBS, peptic ulcers)
- Routine consumption of pre and/or probiotic foods or supplements
- On blood thinners
Key Trial Info
Start Date :
December 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06153719
Start Date
December 1 2023
End Date
June 1 2024
Last Update
December 8 2023
Active Locations (1)
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1
Nottingham Trent University - Clifton campus
Nottingham, United Kingdom