Status:
COMPLETED
Risk of NSAIDs on Anastomotic Leak for Rectal Surgery
Lead Sponsor:
Third Military Medical University
Conditions:
Anastomotic Leak
Anti-Inflammatory Agents, Non-Steroidal
Eligibility:
All Genders
18+ years
Brief Summary
Conflicting reports of the association between early postoperative non-steroidal anti-inflammatory drugs (NSAIDs) administration and anastomotic leak (AL) after rectal surgery have continued. The defi...
Detailed Description
Concerning about the side effects induced by opioids, nonsteroidal anti-inflammatory drugs (NSAIDs) have gained its popularity in ERAS protocols. NSAIDs competitively inhibits the activity of cyclooxy...
Eligibility Criteria
Inclusion
- Biopsy-proven adenocarcinoma of the rectum
- Age over 18 years old
- Patients underwent non-emergency minimally invasive surgery with a primary anastomosis
Exclusion
- Incomplete medical records
- Patients with distant metastasis before surgery
- Patients with multiple primary colorectal carcinomas
Key Trial Info
Start Date :
May 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 25 2024
Estimated Enrollment :
1969 Patients enrolled
Trial Details
Trial ID
NCT06155175
Start Date
May 1 2023
End Date
February 25 2024
Last Update
May 7 2025
Active Locations (1)
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1
Army Medical Center
Chongqing, None Selected, China