Status:
UNKNOWN
Effects of Prebiotics on Metagenomic Diversity and Abundance in Young Children With Acute Malnutrition
Lead Sponsor:
University of the Punjab
Collaborating Sponsors:
University of Veterinary and Animal Sciences, Lahore - Pakistan
Conditions:
Child Malnutrition
Eligibility:
All Genders
6-59 years
Phase:
NA
Brief Summary
Malnutrition is a major global public health issue, contributing to poor health and early morbidities in children under five, particularly in developing countries. In 2021, 5 million children died wor...
Detailed Description
Metagenomics is the study of microorganisms' genomes through the direct extraction and cloning of their DNA from a collection of microorganisms, also known as environmental and community genomics. The...
Eligibility Criteria
Inclusion
- Inclusion criteria: Age 6-59 months at enrolment;
- Acute malnutrition without complications, as defined by the World Health Organization (i.e., children with mid-upper arm circumference (MUAC) \<115 mm or weight-for-height z-score \<-3 or grade 1-2 bilateral edema who will be clinically well and alert with good appetite);
- Parental consent for the child to participate.
- Healthy children without any chronic or acute illness
Exclusion
- Presence of any complications of severe malnutrition (severe dehydration, severe anemia, severe pitting edema, anorexia, hypothermia, high pyrexia, acute lower respiratory infection, or hypoglycemia) or immunocompromised.
- Children on antibiotic treatment for any disease in the last 3 months will be excluded.
Key Trial Info
Start Date :
January 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06155474
Start Date
January 1 2024
End Date
June 1 2024
Last Update
December 4 2023
Active Locations (1)
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1
Department of Public Health, University of the Punjab
Lahore, Pakistan, 54500