Status:

RECRUITING

Russian Registry of Endovascular Closure of PFO

Lead Sponsor:

National Medical Research Center for Cardiology, Ministry of Health of Russian Federation

Conditions:

Patent Foramen Ovale

Eligibility:

All Genders

18-70 years

Brief Summary

The study will include all patients over 18 years of age who underwent endovascular closure of patent foramen ovale in medical centers in the Russian Federation, who gave written informed consent to t...

Detailed Description

Ischemic stroke is the fifth most common cause of death and the leading cause of disability among adult patients worldwide. Cryptogenic stroke is a very broad term that applies in cases of incomplete ...

Eligibility Criteria

Inclusion

  • Patients with an ischemic event (cryptogenic ischemic stroke, transient ischemic attack, embolism of other organs and systems) associated with a PFO;
  • Presence of an open oval confirmed by ultrasound diagnostic methods;
  • Age of patients from 18 years;
  • Life expectancy of at least 1 year;
  • Signed informed consent for endovascular closure of a PFO.

Exclusion

  • Inability to receive antiplatelet therapy;
  • Presence of acute inflammatory diseases;
  • Acute stage of cerebral circulatory failure (30 days);
  • Myocardial infarction or aortocoronary bypass surgery within the previous 30 days;
  • Carotid or vertebral artery dissection;
  • Severe cardiac valve pathology;
  • Presence of blood clots in the cardiac cavities;
  • Refusal of the patient to participate in the study.

Key Trial Info

Start Date :

December 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

700 Patients enrolled

Trial Details

Trial ID

NCT06156670

Start Date

December 1 2023

End Date

December 31 2025

Last Update

January 29 2025

Active Locations (1)

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1

National Medical Research Center for Cardiology, Ministry of Health of Russian Federation

Moscow, Russia