Status:
RECRUITING
Brain Network Analysis of Anesthesia Characteristics in Patients With pDoC Based on PSG
Lead Sponsor:
Beijing Tiantan Hospital
Conditions:
Disorders of Consciousness
Eligibility:
All Genders
18-65 years
Brief Summary
The goal of this prospective, exploratory and observational study is to learn about in healthy volunteers and patients with prolonged disorders of consciousness(pDoC). The main questions it aims to an...
Eligibility Criteria
Inclusion
- Inclusion criteria of health volunteer group:
- Aged 18-65, native Chinese
- No history of sleep apnea
- No history of insomnia
- Volunteer to participate in this study and obtain informed consent.
- Inclusion criteria of pDoC group:
- Aged 18-65, native Chinese
- pDoC after acquired brain injury
- The spinal electric stimulator was implanted under general anesthesia
- Obtain informed consent.
Exclusion
- Healthy volunteers took hypnotic drugs 72 hours before the study
- Continuous sedation treatment was carried out within 72 hours before the study
- The integrity of brain structures such as open head injury and brain parenchyma resection
- Intracranial compliance decreased due to hydrocephalus
- Airway stenosis and severe ventilation or ventilation dysfunction caused by various reasons
- Known or suspected to have serious heart, lung and kidney dysfunction
- Allergic history of sedative drugs
- Combined with other mental or nervous system diseases
- Other reasons are not suitable for this study.
Key Trial Info
Start Date :
January 11 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06157008
Start Date
January 11 2023
End Date
June 1 2025
Last Update
August 1 2024
Active Locations (1)
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1
Beijing Tiantan Hospital
Beijing, China