Status:
UNKNOWN
Vitrification of Oocytes Matured by CAPA-IVM
Lead Sponsor:
Centro de Fertilidad y Reproducción Asistida, Peru
Collaborating Sponsors:
Centro de Estudios e Investigaciones en Biología y Medicina Reproductiva
Conditions:
Fertility Preservation
Eligibility:
FEMALE
20-37 years
Brief Summary
It has been reported that the potential of In Vitro matured oocytes might be affected by the vitrification process. In fact, the freezing and thawing procedures routinely used in IVF laboratories, hav...
Detailed Description
This is a single-center non-blinded observational study. The proposed study will follow a sibling oocyte design in infertile patients. In Vitro Maturation will be performed by using the Capacitation-...
Eligibility Criteria
Inclusion
- Either
- Patients with Polycystic ovary morphology: At least 25 follicles (2-9 mm) throughout the ovary and/or increased ovarian volume (\>10ml) (it is enough for 1 ovary to meet these criteria)
- Patients with good ovarian reserve: High antral follicle count (AFC): ≥ 20 antral follicles in both ovaries or Anti-müllerian hormone (AMH) value ≥3.5 ng/ml
- In both cases, without significant uterine or ovarian anomalies
Exclusion
- There are contraindications for the administration of gonadotropins, oral contraceptives and/or other drugs used in the framework of the present study.
- Preimplantation Genetic Testing (PGT) Cycles
- Oocyte donation cycles
- Medical contraindication for pregnancy.
- High grade endometriosis (\> grade 2)
- Cases with extremely poor sperm
Key Trial Info
Start Date :
December 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06157619
Start Date
December 1 2023
End Date
March 1 2025
Last Update
December 6 2023
Active Locations (1)
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1
Centro de Fertilidad y Reproducción Asistida
Lima, Peru, 15036