Status:

UNKNOWN

Effect of Ultrasound Combined With Microbubbles on Blood Perfusion in Invasive Breast Cancer

Lead Sponsor:

Beijing Friendship Hospital

Conditions:

Invasive Breast Cancer

Cavitation

Eligibility:

All Genders

18+ years

Brief Summary

Blood perfusion insufficiency and hypoxia are the main causes of drug resistance to chemotherapy in breast cancer. Increasing blood perfusion can improve drug delivery. The cavitation effect of ultras...

Detailed Description

patients with IBC were selected from the breast surgery department of our hospital. To induce an enhanced perfusion effect, IBC tumors were treated with SonoVue® microbubbles (MBs) stimulated by ultra...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of Invasive Breast Cancer
  • patients scheduled to undergo surgical resection
  • maximum lesion diameter \< 4 cm
  • age over 18 years

Exclusion

  • patients with allergies to SonoVue®
  • patients with severe cardiopulmonary insufficiency,
  • patients who had already received neoadjuvant chemotherapy
  • pregnant women
  • individuals with mental illness
  • Patients who refused to participate in the study

Key Trial Info

Start Date :

September 29 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 6 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06158217

Start Date

September 29 2022

End Date

May 6 2025

Last Update

December 6 2023

Active Locations (1)

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Beijing Friendship Hospital, Capital Medical University

Beijing, China, 100050