Status:
RECRUITING
Conventional Bronchoscope With BAL vs. Thin Bronchoscope With BW to Diagnose Pulmonary TB
Lead Sponsor:
Pusan National University Hospital
Conditions:
Tuberculosis, Pulmonary
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study aims to compare the diagnostic yield of bronchoalveolar lavage (BAL) using a thick conventional bronchoscope and bronchial washing (BW) using a thin bronchoscope in the diagnosis of pulmona...
Detailed Description
In patients with suspected pulmonary tuberculosis (TB), confirm the presence of TB bacilli through sputum testing is essential for diagnosis. However, the sensitivity of sputum specimens is suboptimal...
Eligibility Criteria
Inclusion
- participants age \> 17 years with suspected pulmonary TB
- possible active pulmonary TB evident on chest radiography or CT scan
- negative AFB smear results (using two consecutive self-expectorated sputum)
- negative TB-PCR results (using one self-expectorated sputum)
- inability to produce self-expectorated sputum
Exclusion
- a request for empirical TB treatment rather than bronchoscopy
- suspect pulmonary TB lesions that are difficult to target for BAL or BW (e.g., multiple discrete tiny nodules)
- contra-indication of bronchoscopy (e.g., bleeding tendency, hypoxemia requiring oxygen, or uncontrolled cardio/cerebrovascular disease)
Key Trial Info
Start Date :
December 15 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
132 Patients enrolled
Trial Details
Trial ID
NCT06159023
Start Date
December 15 2023
End Date
December 31 2025
Last Update
April 16 2024
Active Locations (1)
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1
Pusan National University Hospital
Busan, South Korea, 49241