Status:
COMPLETED
Primary Graft Dysfunction, Pronation, Bilateral Lung Transplants
Lead Sponsor:
University of Padova
Conditions:
Lung Transplant
Primary Graft Dysfunction
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Proning manoeuvre as an early treatment for acute severe hypoxic respiratory failure has been implemented recently during the COVID-19 pandemic. This method was proposed more than fifty years ago to i...
Detailed Description
Lung transplant is the final stage of intervention in dramatic respiratory failure unresponsive to other medical or surgical treatments: reduced disability, improved life quality and extended life are...
Eligibility Criteria
Inclusion
- Age \> 18 y.o.
- First bilateral lung transplant
- PGD grade 2 or 3 within 24 hours from ICU admission Admission to ICU for post-operative monitoring after LTx
- Written informed consent obtained
Exclusion
- Age \< 18 years old
- PGD\<2
- Single transplant
- Re-transplant
- IMV, venous-venous (V-V) or venous-arterial (V-A) extracorporeal membrane oxygenation (ECMO) before surgery
- Contraindications to prone positioning
- Refusal of consent
Key Trial Info
Start Date :
January 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 15 2023
Estimated Enrollment :
67 Patients enrolled
Trial Details
Trial ID
NCT06159933
Start Date
January 1 2020
End Date
November 15 2023
Last Update
February 1 2024
Active Locations (1)
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1
Azienda Ospedaliera Università Padova
Padua, Italy, 35126