Status:

UNKNOWN

The Role of NK Cells to Detect Blood Infection in ALL.

Lead Sponsor:

Assiut University

Conditions:

Acute Lymphoblastic Leukemia

Bloodstream Infection

Eligibility:

All Genders

Up to 17 years

Brief Summary

1. Assess possibility of prediction of blood stream infections in ALL patients by profiling of NK cells using flow cytometry. 2. Assess the role of NK cells in development of drug resistance post chem...

Detailed Description

Acute lymphoblastic leukemia (ALL) is the most common malignancy affecting children accounting for approximately 30% of childhood cancers (Zeng XL et al, 2023 ALL is characterized by chromosomal abnor...

Eligibility Criteria

Inclusion

  • Patients aged less than 17 years diagnosed as Acute Lymphoblastic Leukemia and on chemotherapy, who are positive for blood stream infection.

Exclusion

  • Patients over 17 years of age.
  • Presence of other hematological malignancies or history of other malignancies.

Key Trial Info

Start Date :

February 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 1 2025

Estimated Enrollment :

56 Patients enrolled

Trial Details

Trial ID

NCT06160115

Start Date

February 1 2024

End Date

April 1 2025

Last Update

December 7 2023

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