Status:

RECRUITING

Upfront EUS CGN/CPN vs Conventional Step up Approach for Inoperable Painful Pancreatic Cancer

Lead Sponsor:

Chinese University of Hong Kong

Conditions:

Pancreatic Cancer Non-resectable

Tumor Pancreas

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Patients with unresectable pancreatic cancer are often demoralized by intractable, persistent and incapacitating pain. It must be managed aggressively and strong opioids are recommended as the mainsta...

Eligibility Criteria

Inclusion

  • Age \>= 18 years old
  • Diagnosed to have inoperable pancreatic cancer
  • Presence of tumor pain (centrally located, constant, with no other obvious cause) with a VAS \>= 3
  • Karnofsky performance status \>= 60
  • Planned for EUS examination and/or biopsy of the pancreatic tumor

Exclusion

  • Allergy to bupivacaine, or alcohol
  • Potentially operable after neoadjuvant therapy
  • Expected survival of less than 3 months
  • Patient who is already on opioids for pain control
  • Previous percutaneous or EUS-guided CGN/ CPN
  • Recurrent pancreatic tumors after operation
  • Uncorrectable coagulopathy
  • Inability or unwillingness to provide informed consent

Key Trial Info

Start Date :

November 10 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 31 2027

Estimated Enrollment :

94 Patients enrolled

Trial Details

Trial ID

NCT06160323

Start Date

November 10 2023

End Date

July 31 2027

Last Update

December 7 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Prince of Wales Hospital

Hong Kong, Hong Kong, 00000