Status:
COMPLETED
IMRT Versus 3DCRT for Locally Advanced Rectal Cancer, Prospective Phase II Study.
Lead Sponsor:
Rabin Medical Center
Conditions:
Rectal Cancer
Radiotherapy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this prospective phase II study was to determine whether personalized planning-based nCRT for LARC would indeed decrease small bowel dose, and whether selected plans, specifically prioriti...
Detailed Description
The standard of care for locally advanced rectal cancer is neoadjuvant chemoradiotherapy. However, acute gastrointestinal (GI) toxicity is common. Some retrospective studies suggested that Intensity M...
Eligibility Criteria
Inclusion
- Patients with locally advanced rectal adenocarcinoma
- Performance status of 0-2
- Adequate hematologic, renal, and hepatic function
Exclusion
- Prior radiotherapy to pelvis
- Metastatic disease at diagnosis
Key Trial Info
Start Date :
October 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2021
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT06160570
Start Date
October 1 2018
End Date
January 31 2021
Last Update
December 7 2023
Active Locations (1)
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1
Orly Yariv
Petah Tikva, Israel