Status:
COMPLETED
Time-restricted Enteral Nutrition Versus Continuous Enteral Nutrition in Patients With Severe Stroke
Lead Sponsor:
First Affiliated Hospital of Wannan Medical College
Conditions:
Stroke
Time Restricted Feeding
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
In patients with severe stroke whose GCS score is ≤12 points or NIHSS score is ≥11 points, to evaluate whether time-restricted enteral nutrition can improve the incidence of poor 90-day prognosis (mRS...
Detailed Description
Control the daily enteral nutrition time to 8-12 hours, enteral nutrition start time: 06:00 \~ 08:00, end time: 16:00 \~ 18:00. Enteral nutrition lasts until the patient discontinues enteral nutrition...
Eligibility Criteria
Inclusion
- Age ≥18 years old and \<80 years old;
- Cerebral parenchymal hemorrhage or cerebral infarction within 72 hours of onset;
- GCS score ≤12 points or NIHSS score ≥11 points on admission,
- Enteral nutrition is planned, and the estimated enteral nutrition treatment time is ≥7 days;
- Signed informed consent form.
Exclusion
- Complete parenteral nutrition is required due to contraindications to enteral nutrition;
- After gastrectomy or intestinal resection;
- Enteral nutrition treatment has been performed for \>12 hours;
- Accompanying diseases: a. Advanced cancer; b. Severe cardiac insufficiency \[ejection fraction ≤ 50%\]; c. Severe liver failure \[Child Pugh score ≥ 7\]; d. Severe renal failure \[glomerular filtration\] rate ≤ 30 mL/min or serum creatinine ≥ 4 mg/dL\])
- Have a history of mental illness or mRS ≥ 3 points;
- The patient's doctor or nutritional therapist believes that the plan is not in the best interest of the patient;
- During the patient's admission, death is inevitable, and there are underlying diseases that result in a survival time of \<90 days;
- The patient participates in another clinical study.
Key Trial Info
Start Date :
January 15 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 12 2025
Estimated Enrollment :
420 Patients enrolled
Trial Details
Trial ID
NCT06161948
Start Date
January 15 2024
End Date
December 12 2025
Last Update
January 2 2026
Active Locations (1)
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1
The first affliated hospital of Wannan medical college
Wuhu, China