Status:
RECRUITING
Exploring the Benefit of Peripheral Nerve Stimulation in Treating Pain From Chemo-induced Peripheral Neuropathy: A Longitudinal Single Center Feasibility Study
Lead Sponsor:
M.D. Anderson Cancer Center
Conditions:
Peripheral Nerve Stimulation
Chemotherapy-induced Peripheral Neuropathy
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
To learn if peripheral nerve stimulation (PNS) can help to improve pain in participants with CIPN.
Detailed Description
Primary objective: To assess Pain intensity (NRS) scores in chemotherapy induced peripheral neuropathy (CIPN) participants before and after use of peripheral nerve stimulation (PNS). Secondary objec...
Eligibility Criteria
Inclusion
- Participants diagnosed with chronic (≥90 days duration) CIPN (due to either vinca alkaloids, taxanes, bortezomib, thalidomide, platinum-based compounds or ionizing irradiation) of the lower extremity, seen at Pain Management Center at MD Anderson Cancer Center
- Participants reports baseline pain ≥ 4 (0-10 scale, NRS)
- Participants between ages 18-85 years old
- Participants who have completed chemotherapy within the previous year at the time of enrollment
Exclusion
- Participants with cognitive dysfunction
- Participants with recent history (\<6 months) of drug or alcohol abuse
- Participants with open skin lesion or undergoing antibiotic therapy for local for systemic infection
- Participants with allergies to local anesthesia, steroids, or adhesives
- Participants with conditions that conflict with the SPRINT PNS System Indications for Use, including Contraindications and Warnings.
Key Trial Info
Start Date :
February 22 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06162403
Start Date
February 22 2024
End Date
December 31 2027
Last Update
August 26 2025
Active Locations (1)
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1
MD Anderson Cancer Center
Houston, Texas, United States, 77030