Status:
RECRUITING
Appropriate Use of Blood Cultures in the Emergency Department Through Machine Learning
Lead Sponsor:
Amsterdam UMC, location VUmc
Conditions:
Artificial Intelligence
Machine Learning
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this clinical trial is to study whether the use of our blood culture prediction tool is non-inferior to current practice and if it can improve certain outcomes in all adult patients presen...
Detailed Description
Rationale: The overuse of blood cultures in emergency departments leads to low yields and high numbers of contaminated cultures, which is associated with increased diagnostics, antibiotic usage, prolo...
Eligibility Criteria
Inclusion
- Age \>= 18 years
- Have a clinical indication for a blood culture analysis (according to the treating physician)
- Have sufficient data recorded (laboratory results and vital sign measurements) for a prediction to be made (at least 20% of the needed parameters)
Exclusion
- Central Venous Line (CVL) or Peripherally Inserted Central Catheter (PICC) in situ
- Neutrophil count \< 0.5 \* 109/L
- Candidemia or S. aureus bacteraemia in the past 3 months.
- Most likely diagnosis of endocarditis/spondylodiscitis/infected prosthetic material
- Pregnant or breastfeeding patients
- Not capable of giving informed consent
Key Trial Info
Start Date :
February 19 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2027
Estimated Enrollment :
7584 Patients enrolled
Trial Details
Trial ID
NCT06163781
Start Date
February 19 2024
End Date
July 1 2027
Last Update
May 7 2024
Active Locations (1)
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1
Amsterdam UMC - location AMC
Amsterdam, Netherlands