Status:
RECRUITING
A Bidirectional Cohort Study of COMMD10 Expression in Tumor Tissues for Predicting Radiosensitivity
Lead Sponsor:
Nanfang Hospital, Southern Medical University
Conditions:
Biomarker
Radiosensitivity
Eligibility:
All Genders
18+ years
Brief Summary
Radiotherapy is one of the main treatments for malignant tumors, and according to authoritative estimates, about 70% of patients with malignant tumors should receive radiotherapy. However, radiation r...
Eligibility Criteria
Inclusion
- At least 18 years old;
- Voluntarily sign informed consent;
- Nasopharyngeal carcinoma, head and neck tumor, lung cancer, breast cancer, stomach cancer, colorectal cancer, glioma, esophageal cancer, liver cancer, bile duct cancer, cervical cancer, prostate cancer confirmed by pathology;
- Measurable tumor lesions according to RECIST v1.1 criteria;
- Patients with radiation therapy indications and voluntarily accept radiotherapy;
- ECOG PS score: 0/1.
Exclusion
- There are contraindications to radiotherapy;
- Pathological sections could not be obtained;
- Presence of metal metabolism-related diseases such as Wilson's disease;
- Merge other tumors (has cured basal cell or squamous cell cancer, and cervical cancer in situ except 5);
- Patients had any serious coexisting medical conditions that could pose an unacceptable risk or negatively affect trial adherence. "For example, unstable heart disease requiring treatment, chronic hepatitis, kidney disease, poor health status, uncontrolled diabetes (fasting blood glucose \> 1.5 × ULN), and mental illness;"
- The investigator judged that he was not suitable to participate in the study.
Key Trial Info
Start Date :
December 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2025
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT06165224
Start Date
December 1 2023
End Date
June 30 2025
Last Update
March 15 2024
Active Locations (1)
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1
Nanfang hospital, Southern medical university
Guangzhou, Guangdong, China, 510515