Status:

COMPLETED

The Use of Platelet-rich-fibrin in Lower Third Molar Surgery.

Lead Sponsor:

Amerigo Giudice

Conditions:

Facial Swelling

Tooth Position Anomalies

Eligibility:

All Genders

18-32 years

Phase:

NA

Brief Summary

The present study aims to analyze the effect of PRF (Platelet-rich-fibrin) in terms of facial swelling, trismus and pain after surgical removal of mandibular third molar (M3M) in a split-mouth randomi...

Detailed Description

The present study aims to analyze the effect of PRF (Platelet-rich-fibrin) in terms of facial swelling, trismus and pain after surgical removal of mandibular third molar (M3M) in a split-mouth randomi...

Eligibility Criteria

Inclusion

  • Patients aged 18 to 32 years who required both M3M extractions were recruited
  • Good health status
  • Indication to surgical extraction of both M3M
  • Complete root formation
  • Surgical risk level classified as "Conventional" or "Moderate" according to Daugela et al. classification

Exclusion

  • Person under the age of 18 or over 32
  • Allergy or contraindications to administration of corticosteroids
  • Acute infection in any of the teeth to be extracted
  • Patients with chronic liver disease, diabetes, immune system dysfunction, or haematological disease
  • Pregnancy or breastfeeding
  • History of treatment with antiresorptive drugs
  • Chronic kidney disease

Key Trial Info

Start Date :

October 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 31 2023

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT06165692

Start Date

October 1 2022

End Date

October 31 2023

Last Update

December 11 2023

Active Locations (1)

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1

Magna Graecia University of Catanzaro

Catanzaro, Italy, 88100