Status:
RECRUITING
NBI Combined With MRI to Guide CTV Optimization in Eccentric Nasopharyngeal Carcinoma
Lead Sponsor:
Chongqing University Cancer Hospital
Conditions:
Nasopharyngeal Carcinoma by AJCC V8 Stage
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is a prospective, single-center clinical trial in eccentric nasopharyngeal carcinoma (NPC) patients. The aim of this study is to evaluate the efficacy and safety of NBI combined with MRI-guided o...
Detailed Description
All patients with eccentric nasopharyngeal carcinoma were selected on the basis of MRI findings and NBI endoscopy was performed in these patients. The patients were enrolled if both NBI endoscopy and ...
Eligibility Criteria
Inclusion
- Males and females ≥18 years of age;
- ECOG Performance Status 0,1 or 2;
- Pathologically diagnosed as nasopharyngeal carcinoma;
- Pretreatment nasopharynx and neck MRI imaging;
- Nasopharyngeal suspected lesions were examined by NBI endoscopy;
- Meeting the definition of eccentric NPC with ipsilateral (affected side) staging of T1-4 and contralateral (healthy side) staging of T0;
- Patients evaluated without contraindications to radiotherapy;
- Voluntary participation in clinical research, and signed informed consent.
Exclusion
- Patients who did not successfully undergo all three examinations (MRI, NBI, and endoscopic biopsy);
- Other rare pathological types, such as adenocarcinoma;
- Patients with tumor invasion of the clivus;
- Patients whose contralateral retropharyngeal lymph nodes met the diagnostic criteria;
- Invasion of paranasal sinuses (except simple sphenoid invasion).
Key Trial Info
Start Date :
October 20 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06167109
Start Date
October 20 2023
End Date
October 1 2026
Last Update
December 12 2023
Active Locations (1)
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1
Chongqing University Cancer Hospital
Chongqing, Chongqing Municipality, China, 400030