Status:

NOT_YET_RECRUITING

CAtaract ASSessment of IntrOcular Lens Objective PErformancE

Lead Sponsor:

Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts

Collaborating Sponsors:

Fondation Ophtalmologique Adolphe de Rothschild

StreetLab Vision

Conditions:

Cataract

Eligibility:

All Genders

65-75 years

Phase:

NA

Brief Summary

Prospective, interventional, non-invasive, monocentric, longitudinal, non-randomized study

Detailed Description

There are many strategies for restoring vision after cataract surgery. They all involve the use of intraocular lenses (IOLs) to correct a single focal length (monofocal lenses) or several focal length...

Eligibility Criteria

Inclusion

  • Male / Female
  • 65-75 years old
  • Pseudophakia, implanted with 2 trifocal IOL or 2 EDOF IOL or with 2 monofocal IOL calculated for monovision
  • Second eye surgery performed \> 1 month before inclusion with stable residual refraction
  • No degenerative or neurological disease
  • Good understanding of the French language
  • No use of an aid to locomotion (example: cane, etc...)
  • Binocular far non corrected visual acuity ≥ 8/10
  • Refraction at distance vision
  • Spherical equivalent in distance vision ≤ 0.75 diopter
  • Cylinder ≤ 0.75 diopter
  • Monovision group :
  • \> Addition=1.25 diopter ±0.50
  • Multifocal group :
  • Monocular far non corrected visual acuity ≥ 8/10
  • ATLISA tri (Zeiss)
  • EDOF group :
  • Monocular far non corrected visual acuity ≥ 8/10
  • Eyehance (J\&J)

Exclusion

  • Media opacity or eye movement disorder (nystagmus) that interferes with retinal imaging data quality in the opinion of the investigator ;
  • Media opacity or eye movement disorder (nystagmus) that interferes with retinal imaging data quality in the opinion of the investigator ;
  • Any concurrent intraocular condition that, in the opinion of the investigator would either require surgical intervention during the study to prevent or treat visual loss that might result from that condition or affect interpretation of study results ;
  • Known systemic illness which in the opinion of the investigator will prevent from actively participating in the study ;
  • Concomitant treatment in either eye (concomitant use of vitamins/supplements is not excluded) ;
  • Inability to comply with study task instructions or study visits ;
  • Medication that may cause motor, visual or cognitive impairment (PSAs, neuroleptics, etc.) or interfere with study evaluations ;
  • Other uncontrolled ophthalmic conditions that may interfere with study evaluation ;
  • Participation in another clinical trial that may interfere with the present study ;
  • Cognitive impairment, illiteracy, and subjects who do not speak the national language ;
  • Paralysis may compromise ability to perform manual grasping tasks ;
  • Pregnant or breastfeeding woman ;
  • Patient under legal protection ("curatelle" or "tutelle") ;
  • Patient denied freedom by a legal or administrative order.

Key Trial Info

Start Date :

January 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT06168617

Start Date

January 1 2024

End Date

January 1 2026

Last Update

December 19 2023

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CAtaract ASSessment of IntrOcular Lens Objective PErformancE | DecenTrialz