Status:

ACTIVE_NOT_RECRUITING

E-cigarette Harm Reduction Among PLWHA in South Africa

Lead Sponsor:

NYU Langone Health

Collaborating Sponsors:

Fogarty International Center of the National Institute of Health

Conditions:

Tobacco Smoking

Eligibility:

All Genders

18-70 years

Phase:

PHASE1

Brief Summary

The purpose of this pilot randomized controlled trial study aims to address the unmet need for feasible and efficacious strategies for reducing combustible cigarette (CC) use among people living with ...

Eligibility Criteria

Inclusion

  • Adult PLWHA CC smokers;
  • Speaks Afrikaans, or Xhosa, or English;
  • reports daily CC smoking (≥ 5 CPD);
  • Owns any type of mobile phone;
  • interested in reducing CC smoking but not necessarily trying to quit;
  • Receives HIV/AIDS care in one of the eight selected clinics follow-up rates.

Exclusion

  • are pregnant or breastfeeding;
  • unable to provide consent;
  • used tobacco products other than CC in the past 2 weeks (e.g., EC, cigarillo);
  • currently engaged in an attempt to quit CC smoking;
  • current major depressive or manic episode, current psychotic disorder, past-year suicide attempt, or current suicidal ideation with plan or intent. plan or intent.

Key Trial Info

Start Date :

April 15 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 27 2026

Estimated Enrollment :

106 Patients enrolled

Trial Details

Trial ID

NCT06169813

Start Date

April 15 2025

End Date

February 27 2026

Last Update

November 3 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

South African Medical Research Council (SAMRC)

Cape Town, South Africa, 7501