Status:
COMPLETED
Effect of Topical Agents With Various Antioxidant Containts on Photodamage Skin Induced
Lead Sponsor:
Universitas Padjadjaran
Conditions:
Photodamaged Skin
Eligibility:
All Genders
18-60 years
Phase:
PHASE2
Brief Summary
Ultraviolet (UV) irradiation of the skin leads to acute inflammatory reactions such as erythema, sunburn, and chronic reactions, including premature skin aging and skin tumors. UV irradiation is a pot...
Detailed Description
Photoprotection is an effort made to reduce the detrimental effects of Reactive Oxygen Species (ROS) on the skin due to UVB exposure. Photoprotection consists of primary and secondary. Lifestyle modif...
Eligibility Criteria
Inclusion
- Males and females aged 18-60 years.
- Skin types III and IV according to Fitzpatrick.
- Normal back skin.
Exclusion
- Pregnant and lactating women.
- History of photodermatosis, skin malignancies, skin diseases that can be exacerbated by light.
- History of sun exposure to the back area in the past two weeks.
- History of applying and taking antioxidants containing gluconolactone, hyaluronic acid, allantoin, ferulic acid, acetyl heptapeptide, silver vine extract, ectoine, and hydroxyectoine in the past 12 weeks.
- History of taking photosensitizer drugs (malaria drugs, analgesics, antidepressants, systemic fungal drugs, chemotherapy) in the past eight weeks.
Key Trial Info
Start Date :
November 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2024
Estimated Enrollment :
11 Patients enrolled
Trial Details
Trial ID
NCT06170346
Start Date
November 1 2022
End Date
January 31 2024
Last Update
April 8 2025
Active Locations (1)
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1
Hasan Sadikin General Hospital
Bandung, West Java, Indonesia, 40161