Status:

RECRUITING

POLARx Post Approval Study (POLARx PAS)

Lead Sponsor:

Boston Scientific Corporation

Conditions:

Paroxysmal Atrial Fibrillation

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

To collect clinical data on safety, effectiveness and procedural success of Boston Scientific's Cardiac Cryoablation System (includes all BSC commercially available POLARx/POLARx Fit catheters) when u...

Eligibility Criteria

Inclusion

  • Subjects indicated for drug refractory, recurrent symptomatic PAF treatment with the Cryoablation System, per physician's medical judgement, and as per standard of care
  • Subjects who are willing and capable of providing informed consent;
  • Subjects who are willing and capable of participating in all testing associated with this clinical study at an approved clinical investigational center;

Exclusion

  • Any known contraindication to an AF ablation or anticoagulation, including those listed in the IFU as legally approved conditions;
  • Any prior LA ablation;
  • Known or pre-existing severe PV Stenosis;
  • Subjects with severe valvular disease OR with a prosthetic - mechanical or biological - heart valve (not including valve repair and annular rings);
  • Presence of any pulmonary vein stents;
  • Subjects with active systemic infection;
  • Subject is unable or not willing to complete follow-up visits and examination for the duration of the study;- Subjects with life expectancy ≤ 1 year per investigator's medical judgement;
  • Women of childbearing potential who are, or plan to become, pregnant during the time of the study (assessment per investigator's discretion);

Key Trial Info

Start Date :

June 28 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2029

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06170606

Start Date

June 28 2024

End Date

May 1 2029

Last Update

December 24 2025

Active Locations (11)

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Page 1 of 3 (11 locations)

1

Mercy Gilbert Medical Center

Gilbert, Arizona, United States, 85297

2

Banner University Medical Center Phoenix

Phoenix, Arizona, United States, 85006

3

Pima Heart & Vascular Clinical Research

Tucson, Arizona, United States, 85718

4

Torrance Memorial Medical Center

Torrance, California, United States, 90505