Status:

RECRUITING

Transcutaneous Vagus Nerve Stimulation as a Complementary Therapy to Exercise in Chronic Fatigue

Lead Sponsor:

Centre Hospitalier Universitaire de Saint Etienne

Conditions:

Chronic Fatigue Syndrome

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Chronic fatigue is enhanced by adapted physical activity (APA) programs. Patients consulting on St Etienne hospital and suffering from fibromyalgia and long Covid benefit from a 4-6 week APA program, ...

Eligibility Criteria

Inclusion

  • Patient over 18 years old
  • Signature of informed consent
  • Confirmed diagnosis of fibromyalgia or long Covid (ACR 2016 criteria and persistent symptoms lasting more than 6 months after a positive RT-PCR test, respectively)
  • Persistent fatigue after an exercise rehabilitation program (FSS score \> 36)
  • Physical inactivity, i.e. \<150 minutes per week of physical activity

Exclusion

  • Pre-existing atrial fibrillation,
  • Left ventricular ejection fraction \<40%
  • Severe heart failure
  • Recent stroke or myocardial infarction (\<6 months)
  • Unilateral or bilateral vagotomy
  • Pregnancy or breastfeeding

Key Trial Info

Start Date :

October 3 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2026

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06170645

Start Date

October 3 2024

End Date

August 1 2026

Last Update

April 8 2025

Active Locations (1)

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1

Centre Hospitalier de Saint-Etienne

Saint-Etienne, France, 42055