Status:

COMPLETED

Molecular Markers of Acute Kidney Injury in Elderly Deceased Donors

Lead Sponsor:

Institute for Clinical and Experimental Medicine

Conditions:

Kidney Transplantation

Acute Kidney Injury

Eligibility:

All Genders

Brief Summary

Scoring systems that combine donor clinical and morphological parameters to predict outcome of kidney transplantation lack enough specificity to be generally accepted. Compare to classical histology, ...

Detailed Description

The aim is to create a prediction model of early clinical outcome (delayed graft function) based on donor and recipient clinical variables, donor eGFR, urinary AKI biomarkers, histology (glomeruloscle...

Eligibility Criteria

Inclusion

  • All DBD (donation after brain death) donors whose kidneys will be procured by transplant team of Institute for Clinical and Experimental Medicine (IKEM) in donor hospital.
  • All DBD (donation after brain death) donors whose kidneys will be procured by transplant team of Institute for Clinical and Experimental Medicine (IKEM) at IKEM.

Exclusion

  • Donors with circulatory death
  • Donors with machine perfusion
  • Donors with multiorgan transplantation.

Key Trial Info

Start Date :

June 11 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 31 2023

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06171438

Start Date

June 11 2021

End Date

October 31 2023

Last Update

December 14 2023

Active Locations (1)

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Institute for Clinical and Experimental Medicine

Prague, Czechia, 140 21