Status:

COMPLETED

Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors

Lead Sponsor:

UNC Lineberger Comprehensive Cancer Center

Conditions:

Cancer

Physical Activity

Eligibility:

All Genders

18-39 years

Phase:

NA

Brief Summary

The purpose of this study is to conduct a 6-month pilot randomized trial to determine the feasibility and acceptability of theory-based mobile weight loss interventions for survivors of adolescent and...

Detailed Description

The purpose of this study is to conduct a 6-month pilot randomized trial to determine the feasibility and acceptability of three adapted theory-based, mobile weight loss interventions delivered via a ...

Eligibility Criteria

Inclusion

  • In order to participate in this study a subject must meet all of the eligibility criteria outlined below.
  • Currently age 18-39
  • Diagnosed with first invasive cancer between the ages of 15-39 years old
  • Within 10 years of diagnosis with no evidence of progressive disease or second primary cancers
  • Completed active cancer-directed therapy (cytotoxic chemotherapy, radiation therapy, and/or definitive surgical intervention) at least six months prior to enrollment, except maybe receiving "maintenance" therapy to prevent recurrences
  • Body Mass Index (BMI) of 25-50 kg/m2

Exclusion

  • Type 1 diabetes or currently receiving medical treatment for Type 2 diabetes
  • Report a history of heart attack or stroke within the previous 6 months
  • Health problems that preclude the ability to walk for physical activity
  • Lost 5% or more of body weight (and kept it off) in the last 3 months
  • Past diagnosis of or receiving treatment for a clinically diagnosed eating disorder (anorexia nervosa or bulimia nervosa) or any compensatory behaviors within the previous 3 months
  • Currently pregnant, pregnant within the past 6 months, or planning to become pregnant within the next 6 months
  • Untreated thyroid disease or any changes (type or dose) in thyroid medication in the last 6 months
  • Hospitalization for depression or other psychiatric disorder within the past 12 months
  • History of psychotic disorder or bipolar disorder
  • Currently participating in a weight loss, nutrition, or physical activity study or program or other study that would interfere with this study
  • Currently using prescription medications with known effects on appetite or weight.
  • Previous surgical procedure for weight loss or planned weight loss surgery in the next 6 months
  • Inability to speak and read English
  • Do not have an iPhone with active data and text messaging plan
  • No Internet access
  • Not willing to be randomized to either intervention arm

Key Trial Info

Start Date :

March 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 5 2025

Estimated Enrollment :

63 Patients enrolled

Trial Details

Trial ID

NCT06171945

Start Date

March 1 2024

End Date

October 5 2025

Last Update

October 27 2025

Active Locations (1)

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1

Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill

Chapel Hill, North Carolina, United States, 27599