Status:
COMPLETED
Evaluation of Antimicrobial Efficacy and Postoperative Pain After Using Silver Nanoparticles and Chitosan Nanoparticles Against Enterococcus Faecalis and Candida Albicans Biofilm
Lead Sponsor:
Minia University
Conditions:
Endodontic Disease
Eligibility:
All Genders
20-40 years
Phase:
NA
Brief Summary
Silver nanoparticles possess unique physicochemical and biological properties in addition to their antibacterial capabilities. Similarly, zinc oxide nanoparticles have demonstrated antibacterial effec...
Eligibility Criteria
Inclusion
- Medically stable healthy patients (category: American society of anesthesiologists class I).
- The patient ranges in age from 20 to 40.
- No sexual orientation
- Necrotic pulp evaluated by thermal or electrical pulp testing.
- Enough crown structure to provide adequate isolation.
- One root and one canal.
- Patients' desire to engage in this research.
- Patients' comprehension of the visual analogue scale (VAS).
- Patients' ability to sign informed consent.
Exclusion
- Endodontic treatment for the tooth previously.
- Teeth with poor conditions for using rubber dams.
- Vital pulp tissue was observed throughout the treatment.
- Patients who have a medical condition.
- Teeth with open apices that are immature
- Women who are pregnant or breastfeeding.
- Psychologically disturbed patients.
- Patients having a history of allergy to any of the research drugs were barred from participation.
- A periodontally affected tooth with grade 2 or 3 mobility.
Key Trial Info
Start Date :
January 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2023
Estimated Enrollment :
78 Patients enrolled
Trial Details
Trial ID
NCT06172023
Start Date
January 1 2020
End Date
March 1 2023
Last Update
December 15 2023
Active Locations (1)
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1
Faculty of Dentistry, Minia University
Minya, Egypt, 2431412