Status:

NOT_YET_RECRUITING

The Effects of the Otago Exercise Program

Lead Sponsor:

Istanbul University - Cerrahpasa

Conditions:

Pulmonary Arterial Hypertension

Heart Defects, Congenital

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The objective of this experimental study is to conduct a comparative evaluation of the effects of a supervised Otago Exercise Program (OEP) functional exercise capacity, blood lactate levels, dyspnea,...

Detailed Description

Pulmonary hypertension (PH) is characterized by a mean pulmonary artery pressure exceeding 20 mmHg, as measured during heart catheterization. In patients with PH, a pulmonary artery wedge pressure of ...

Eligibility Criteria

Inclusion

  • Being clinically and hemodynamically stable.
  • Resting mean pulmonary artery pressure measured with left heart catheterization to be 20 mmHg or higher.
  • Being 18 years of age or older.
  • Being classified as World Health Organization-functional class II and III.
  • Being under optimized advanced medical treatment for PAH for at least 2 months before entering the study.
  • No changes in pulmonary arterial hypertension medical treatment for at least 6 months before entering the study.

Exclusion

  • The coexistence of Down syndrome.
  • Group 1 PAH patients with another etiology.
  • Changes in PAH medical treatment during follow-up.
  • Acute decompensated heart failure.
  • Unstable angina pectoris.
  • Recent thoracic or abdominal surgeries.
  • Using immunosuppressive drugs due to organ or tissue transplantation.
  • Heavy neurological disorders causing autonomic dysfunction.
  • The presence of cognitive impairment preventing communication.
  • Recent syncope, fractures, osteoporosis, presence of tumors, pregnancy.

Key Trial Info

Start Date :

February 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2026

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06172790

Start Date

February 1 2024

End Date

February 1 2026

Last Update

December 22 2023

Active Locations (1)

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Istanbul University - Cerrahpasa (IUC) Cardiology Institute

Istanbul, Fatih, Turkey (Türkiye)