Status:

COMPLETED

A Relative Bioavailability Study of LY3454738 in Healthy Participants

Lead Sponsor:

Eli Lilly and Company

Conditions:

Healthy

Eligibility:

All Genders

18-65 years

Phase:

PHASE1

Brief Summary

The main purpose of this study is to look at the amount of the study drug, LY3454738 that gets into the blood stream and how long it takes the body to get rid of it when given under the skin comparing...

Eligibility Criteria

Inclusion

  • Participants who are overtly healthy as determined by medical history and physical examination.
  • Have body mass index (BMI) between 18.0 and 28.0 kilograms per meter squared (kg/m²), inclusive, at screening.

Exclusion

  • Have a significant history of or current cardiovascular, respiratory, hepatic, renal, gastrointestinal, endocrine, hematological, or neurological disorders capable of significantly altering the absorption, metabolism, or elimination of drugs; of constituting a risk when taking the investigational medicinal product; or of interfering with the interpretation of data.
  • Had any surgical procedure (except for minor surgery requiring local or no anesthesia and without any complications or sequelae) within 12 weeks prior to screening or intend to during the study.
  • Show evidence of active or latent TB.
  • Have one of the following infections: hepatitis B virus or human immunodeficiency virus (HIV).
  • Participants must not be currently participating in or completed a clinical trial within the last 30 days

Key Trial Info

Start Date :

January 12 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 2 2024

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06173895

Start Date

January 12 2024

End Date

May 2 2024

Last Update

May 30 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

ICON Early Phase Services

San Antonio, Texas, United States, 78209