Status:

RECRUITING

Effect of Psychedelic VR-augmented Therapy on Patients With Clinical Depression

Lead Sponsor:

University of Tartu

Collaborating Sponsors:

Confido Medical Centre

Conditions:

Depression

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Research has demonstrated that psychedelic compounds possess significant therapeutic potential for a variety of disorders, including depression. Despite these findings, the underlying mechanisms drivi...

Eligibility Criteria

Inclusion

  • Persistent depressive symptoms observed during the initial screening and confirmed at baseline, as determined through a comprehensive psychiatric evaluation.
  • Provision of written informed consent by the participant.
  • Fluent in Estonian as a native language.

Exclusion

  • Presence of significant impairments in vision, hearing, or balance.
  • Active suicidal ideation or current engagement in self-harm behaviors. Note: Individuals meeting this criterion will be directed to suitable crisis intervention services.
  • Established diagnosis of bipolar disorder.
  • Manifestation of psychotic symptoms.
  • History of schizophrenia, either personally or within two generations of the family lineage.
  • Ongoing diagnosis of epilepsy, dementia, or any other neurological condition that could interfere with the effective utilization of virtual reality (VR) technology.
  • Susceptibility to motion sickness.

Key Trial Info

Start Date :

November 6 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2026

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT06174285

Start Date

November 6 2023

End Date

June 30 2026

Last Update

March 25 2025

Active Locations (1)

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Confido Medical Centre

Tallinn, Harju, Estonia, 10138