Status:
UNKNOWN
Lung Overdistension and Abdominal Pressure Rise
Lead Sponsor:
University of Padova
Conditions:
Respiratory Failure
Respiratory Distress Syndrome, Adult
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this pilot interventional no-profit study is to evaluate airway pressure, esophageal pressure and variations in lung volume distribution with EIT in mechanically ventilated patients admitt...
Eligibility Criteria
Inclusion
- Invasive mechanical ventilation in acute respiratory failure (PaO2/FiO2 \<300 mmHg)
- Need of PEEP trial
- Need of urinary catheter (used to measure IAP)
Exclusion
- Contraindication to EIT use
- Pacemaker or other metal device in thoracic region
- Contraindication to abdominal weight placement
- Surgical or traumatic incision on the abdomen
- Severe abdominal hypertension
- Esophageal diseases that counterindicate naso-gastric tube placement
- Severe hemodynamic instability (norepinephrine \> 0.1 mcg/kg/min; dobutamine or dopamine \> 5 mcg/kg/min; epinephrine every dosage)
- Severe obesity (BMI \> 35 kg/m2)
- Need of \> 7 kg weight to reach 5 mmHg IAP increase
Key Trial Info
Start Date :
June 20 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06174636
Start Date
June 20 2023
End Date
June 1 2025
Last Update
December 18 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Azienda Ospedaliera Università di Padova
Padua, Italy, 35100