Status:

NOT_YET_RECRUITING

Role of BMP Pathway in MDS Progression

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Myelodysplastic Syndromes

Acute Myelogenous Leukemia

Eligibility:

All Genders

20+ years

Brief Summary

Myelodysplastic syndromes (MDS) are hematological cancers that can progress to acute myelogenous leukemia (AML). The involvement of the microenvironment in the maintenance, resistance and evolution of...

Eligibility Criteria

Inclusion

  • Adult patients with myelodysplastic syndrome or suspected myelodysplastic syndrome according to the criteria defined by the World Health Organization Or
  • Adult patient with suspicion of de novo acute myeloid leukemia at initial treatment

Exclusion

  • Frontier MDS/myeloproliferative syndromes including chronic myelomonocytic leukemia
  • MDS and AML having already benefited from cytotoxic treatment including hydroxycarbamide, azacytidine, intensive chemotherapy
  • Patients objecting to their inclusion in the study
  • Pregnant or breastfeeding women
  • Patients under legal protection measure

Key Trial Info

Start Date :

January 27 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 27 2034

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06175923

Start Date

January 27 2024

End Date

January 27 2034

Last Update

January 23 2024

Active Locations (1)

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1

Hospices Civils de Lyon

Lyon, France, 69229