Status:
COMPLETED
Low vs Standard Local Anesthetics Boluses for Continuous Adductor Canal Block in Total Knee Arthroplasty
Lead Sponsor:
Chulalongkorn University
Conditions:
Knee Arthropathy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
To investigate the efficacy of two different regimens of local anesthetic boluses for continuous adductor canal block under ultrasound-guidance in total knee arthroplasty at King Chulalongkorn Memoria...
Detailed Description
Total knee arthroplasty (TKA) is a commonly performed surgical procedure for patients with severe knee osteoarthritis. However, one of the challenges associated with TKA is the significant postoperati...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Patients undergoing TKA aged more than 18 years
- Patients with American Society of Anesthesiologists (ASA) class 1-3
- Patients with body weight index (BMI) 18-40 kg/m2
- Exclusion Criteria
- Patient refusal to participate
- Patients with known allergic to medications used in the research protocol
- Patients with contraindications to neuraxial or regional anesthesia, including existing neuropathy or neurological deficits involving the lower extremities, coagulopathy or bleeding diathesis and local skin infections
- Patients with contraindications to NSAIDs such as history of coronary artery bypass graft surgery, congestive heart failure, stroke, gastrointestinal bleedings or ulceration, asthma, hepatic and renal disease, abnormal coagulation, or pregnancy
- Patients with chronic opioid use (opioids have been used daily or almost daily for more than three months or sixty milligrams or more of morphine has been used daily for more than one month) or diagnosed with neuropathic pain
- Patients that are unable to perform preoperative Quantitative sensory testing.
Exclusion
Key Trial Info
Start Date :
December 9 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 24 2024
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT06179628
Start Date
December 9 2023
End Date
July 24 2024
Last Update
August 12 2024
Active Locations (1)
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1
Chulalongkorn University
Bangkok, Thailand, 10310