Status:

COMPLETED

Use of Ketamine for Conscious Sedation in Flexible Bronchoscopy

Lead Sponsor:

Brooke Army Medical Center

Conditions:

Conscious Sedation

Patient Satisfaction

Eligibility:

All Genders

18-75 years

Phase:

PHASE4

Brief Summary

In this study, the investigators plan to conduct a single blinded randomized controlled trial in the Pulmonary Service to demonstrate the efficacy of ketamine and its utility in moderate sedation. Pat...

Detailed Description

The investigators propose to carry out a single blinded randomized controlled trial where 33 patients will receive midazolam and ketamine for sedation in one arm and 33 will receive the standard fenta...

Eligibility Criteria

Inclusion

  • Patients age 18 to 75 years who present to the pulmonary clinic for bronchoscopy and considered for airway survey, transbronchial biopsy, endobronchial biopsy, or bronchoalveolar lavage.
  • Provider performing the bronchoscopy

Exclusion

  • Systolic blood pressure over 180mmHg and/or diastolic blood pressure over 110 on two consecutive readings
  • Tachycardia greater than 120 beats/minute on two consecutive measurements
  • Any allergy to ketamine, fentanyl, or midazolam
  • Patient is pregnant or refuses pregnancy test,in women of child-bearing potential\*
  • American Society of Anesthesiologists (ASA) score \> 3
  • Presence of a history of psychosis, hallucinations, and/or a psychotic disorder

Key Trial Info

Start Date :

July 15 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 30 2023

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT06181188

Start Date

July 15 2019

End Date

October 30 2023

Last Update

December 26 2023

Active Locations (1)

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1

Brooke Army Medical Center

San Antonio, Texas, United States, 78234