Status:
RECRUITING
Effects of Individualized PEEP Guided by Driving Pressure on Postoperative Atelectasis in Patients With Morbid Obesity
Lead Sponsor:
Yongtao Sun
Conditions:
Pulmonary Atelectasis
Obesity, Morbid
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Atelectasis is a common complication in patients undergoing surgery under general anesthesia, particularly in obese patients. Postoperative atelectasis could last for more than 24h and contribute to a...
Detailed Description
Positive end-expiratory pressure (PEEP) is a strategy that helps to keep alveoli open during surgery and to prevent postoperative atelectasis. A fixed PEEP without considering the respiratory mechanic...
Eligibility Criteria
Inclusion
- Age 18 to 60 years old;
- Body mass index (BMI) ≥ 40 kg/m2;
- ASA classification I to III;
- Signing the informed consent form for this clinical study;
Exclusion
- Respiratory infection within 4 weeks; severe respiratory system diseases; history of pulmonary and/or thoracic surgery; neuromuscular dysfunction;
- Serious cardiac, renal or haematopoietic diseases;
- Contraindications to PEEP；
Key Trial Info
Start Date :
March 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT06181279
Start Date
March 1 2024
End Date
December 31 2024
Last Update
June 4 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Qianfoshan Hospital, The First Hospital affiliated of Shandong First Medical University
Jinan, Shandong, China, 250014