Status:

RECRUITING

Anticipating Decline and Providing Therapy

Lead Sponsor:

Wake Forest University Health Sciences

Collaborating Sponsors:

National Institute on Aging (NIA)

Conditions:

Cognitive Impairment

Dementia

Eligibility:

All Genders

60+ years

Phase:

NA

Brief Summary

This pilot feasibility study will be a randomized control trial of usual care following Intensive Care Unit (ICU) discharge compared to the Anticipating Decline and Providing Therapy (ADAPT) screening...

Detailed Description

Anticipating Decline and Providing Therapy (ADAPT) is a program designed to support the implementation of a routine post-ICU cognitive impairment screening and support intervention. The program includ...

Eligibility Criteria

Inclusion

  • Age 60 and older at time of discharge from intensive care unit
  • Minimum 72 hour Intensive Care Unit stay in an ICU at Atrium Health Wake Forest Baptist
  • Delirium during ICU stay as determined by positive Confusion Assessment Method (CAM)-ICU score, review of clinical - documentation, or discussion with clinical team
  • Primary care provider in the Atrium Health Wake Forest system or intention to follow with Primary Care Physician in Atrium Health system
  • English speaking

Exclusion

  • Death during initial hospitalization and/or discharge to Hospice
  • Life-expectancy \< 6 months from pre-existing illness (defined as diagnosis of metastatic cancer, cirrhosis, advanced heart failure, prior palliative care referral)
  • Acute Traumatic Brain Injury
  • Continued residence in skilled nursing facility or rehab that prevents ability to complete study telephone call at time of first cognitive screen attempt
  • Prior history of dementia in electronic health record
  • Language or communication barrier that prohibits intervention participation
  • Participant cannot identify family or caregiver contact or family/caregiver unwilling to participate
  • Subject or legally authorized representative (LAR) decline consent
  • Unstable telephone service for contact after hospital discharge
  • Primary residence outside of North Carolina

Key Trial Info

Start Date :

March 8 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 30 2026

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT06182995

Start Date

March 8 2024

End Date

November 30 2026

Last Update

January 7 2026

Active Locations (1)

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Atrium Health Wake Forest Baptist

Winston-Salem, North Carolina, United States, 27157

Anticipating Decline and Providing Therapy | DecenTrialz