Status:
COMPLETED
Validation of a Low-cost Platelet-Rich Plasma (PRP)
Lead Sponsor:
University of Utah
Conditions:
Platelet-Rich Plasma (PRP)
Knee Osteoarthritis (OA)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Knee osteoarthritis is an extremely common and debilitating condition, more common in women, with an estimated global prevalence of 16%, and as high as 50% by the age of 80. Current management of knee...
Detailed Description
Study Purposes and Objectives: The study will directly address two concerns - proper reporting of PRP composition and greatly decreasing cost. As socioeconomic inequity directly relates to disability...
Eligibility Criteria
Inclusion
- Patients of any adult age with symptomatic Kellgren-Lawrence (K-L) score 1-3 knee OA, based on radiographs within the last six months.
- Patients must have failed at least six weeks of conventional conservative treatments (such as medication or physical therapy).
- Patients with bilateral knee OA will only be eligible if both knees fit the criteria; each knee will count separately.
Exclusion
- Recent (last two years) knee surgery,
- Prior orthobiologic injection(s) into the knee,
- Known major axial deviation (over 30 degrees)
- Known thrombocytopenia (platelets under 50,000), thrombocythemia (platelets over 1,000,000), known platelet disorder (ITP, TTP, or Lowe syndrome)
- Active systemic infection requiring antibiotics, or local infection at the site of injection,
- Non-ambulatory patients,
- Patients seeking care with active litigation pending
- Body mass index (BMI) over 40
- Injection into the affected joint within the last six months
- Oral steroids consumed within the last three months.
Key Trial Info
Start Date :
September 15 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 10 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06184048
Start Date
September 15 2023
End Date
October 10 2024
Last Update
November 17 2025
Active Locations (1)
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1
University of Utah Orthopedic Center
Salt Lake City, Utah, United States, 84108