Status:

UNKNOWN

Prone Position With Different Types of Cushions in Patients With ARDS

Lead Sponsor:

Hospital de Clinicas de Porto Alegre

Conditions:

Prone Position

Acute Respiratory Distress Syndrome

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The prone maneuver is a well-established therapy in ARDS. Traditionally, the maneuver is perform with thoraco-abdominal cushions. The goal of this study is assess, using electrical impedance tomograph...

Detailed Description

The prone position is a ventilatory therapeutic strategy used in the treatment of patients with moderate to severe Acute Respiratory Distress Syndrome (ARDS) that promotes improved oxygenation with co...

Eligibility Criteria

Inclusion

  • Adult patients aged 18 years or more, with
  • moderate or severe acute respiratory distress syndrome (ARDS), and
  • indication of prone position

Exclusion

  • Contra-indication to the prone position: intracranial pressure \> 30 mmHg or cerebral perfusion pressure \< 60 mmHg; massive haemoptysis needing urgent surgical or radiological treatment; tracheal or thoracic surgery in the last 15 days; facial trauma or surgery in the last 15 days; deep venous thrombosis or pulmonary embolism treated in the last 2 days; unstable bone dislocations of rachis, femur, rib cage, pelvis; mean systolic arterial pressure less than 70 mmHg despite vasopressive therapy and pregnancy
  • Severe acute respiratory distress syndrome (ARDS) caused b coronavirus disease 2019 (despite meeting the Berlin criteria for ARDS, their ventilatory mechanics are characterized by nearly normal compliance, something rarely seen in patients with ARDS from other etiologies)
  • contraindications for the use of Electrical Impedance Tomography (EIT) such as presence of a cardiac implantable electronic device
  • Pulmonary transplantation
  • Prone position before enrollment

Key Trial Info

Start Date :

August 15 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT06184490

Start Date

August 15 2023

End Date

December 1 2025

Last Update

December 28 2023

Active Locations (1)

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1

Hospital de Clínicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil, 90035903