Status:
RECRUITING
Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women
Lead Sponsor:
San Diego State University
Conditions:
Bone Disease, Metabolic
Eligibility:
FEMALE
Phase:
NA
Brief Summary
The objective of this study is to examine if calcium and vitamin D supplements and/or prune can prevent bone loss in postmenopausal women.
Detailed Description
Two hundred randomly assigned to one of two treatment groups: 1) 30 g prunes and 2) control (0 g prunes). Both groups received 500 mg calcium and 400 IU Vitamin D as a daily supplement. Blood samples ...
Eligibility Criteria
Inclusion
- Postmenopausal
- BMD t-score is between 0.5 and 2 SD below the mean
- Not on hormone replacement therapy (HRT) and/or other pharmacological agents known to affect bone for at least three months prior to initiation of the study
Exclusion
- Women whose BMD t-score at any site falls below 2.5 SD of the mean
- Subjects receiving endocrine (e.g., prednisone, other glucocorticoids) or neuroactive (e.g., dilantin, phenobarbital) drugs or any drugs known to influence bone and calcium metabolism
- Subjects who smoke cigarettes or vape
- Regular consumption of dried plum or prune juice
Key Trial Info
Start Date :
March 15 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2028
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06184646
Start Date
March 15 2024
End Date
December 1 2028
Last Update
July 2 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
San Diego State University
San Diego, California, United States, 92182-7251