Status:

RECRUITING

Radiation Induced Alterations in Resting State Brain Networks in Pediatric Brain Tumor Patients

Lead Sponsor:

Washington University School of Medicine

Collaborating Sponsors:

United States Department of Defense

The Foundation for Barnes-Jewish Hospital

Conditions:

Brain Tumor, Primary

Eligibility:

All Genders

8-21 years

Brief Summary

With modern therapy, the survival rate for pediatric brain tumor patients has significantly improved, with over 70% of patients surviving their disease. However, this progress often comes at the cost ...

Eligibility Criteria

Inclusion

  • Between 8 and 21 years of age, inclusive
  • Newly diagnosed primary brain tumor of any location and any histology that will be treated with proton radiation therapy
  • Life expectancy of at least one year
  • Able to understand and willing to consent or assent to the research proposed (or that of a legally authorized representative, if applicable), along with consent of legal guardian(s) if applicable

Exclusion

  • Presence of visual impairment to an extent that the patient is unable to complete the computer testing
  • Contraindication to MRI scan (i.e. due to cardiac pacemaker)
  • Presence of programmable shunt or dental braces
  • Requires sedation for MRI scans

Key Trial Info

Start Date :

July 10 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 31 2027

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT06185686

Start Date

July 10 2024

End Date

July 31 2027

Last Update

July 18 2025

Active Locations (1)

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1

Washington University School of Medicine/Saint Louis Children's Hospital

St Louis, Missouri, United States, 63110