Status:

RECRUITING

International Active Surveillance Study: Safety of Estrogen Estetrol (E4) Contraceptive Study (INAS-SEECS)

Lead Sponsor:

Center for Epidemiology and Health Research, Germany

Collaborating Sponsors:

Estetra

Gedeon Richter Plc.

Conditions:

Contraception

Eligibility:

FEMALE

Brief Summary

The combined oral contraceptive (COC) containing estetrol (E4) and drospirenone (DRSP) (E4/DRSP) is a novel oral contraceptive containing a fixed dose of E4 (14.2 mg) and DRSP (3 mg). The proposed stu...

Detailed Description

Rationale and background: The combined oral contraceptive (COC) containing estetrol (E4) and drospirenone (DRSP) (E4/DRSP) is a novel oral contraceptive containing a fixed dose of E4 (14.2 mg) and DRS...

Eligibility Criteria

Inclusion

  • • New users of E4/DRSP or EE/DRSP or EE/LNG or EE/NGM or EE/NETA

Exclusion

  • • Women who have given birth six weeks before treatment starts will be excluded from the study.

Key Trial Info

Start Date :

April 24 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2029

Estimated Enrollment :

68100 Patients enrolled

Trial Details

Trial ID

NCT06186271

Start Date

April 24 2025

End Date

June 1 2029

Last Update

August 20 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Berlin Center for Epidemiology and Health Research

Berlin, State of Berlin, Germany, 10115