Status:
UNKNOWN
A Novel 68Ga Labeled FAP Ligand PET/CT in Patients With Various Malignant Tumors
Lead Sponsor:
Guangdong Provincial People's Hospital
Collaborating Sponsors:
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Conditions:
Cancer
Malignant Neoplasm
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The investigators designed and synthesized a novel fibroblast activation protein (FAP) ligand (DOTA-GPFAPI-04) by assembling three functional moieties: a quinoline-based FAP inhibitor for specifically...
Detailed Description
At the beginning of 2022, the National Cancer Center released the latest statistical data showing that the incidence rate of malignant tumors in China reached 293.91/100000, and the mortality rate rea...
Eligibility Criteria
Inclusion
- Patients with high clinical suspicion of malignant tumors;
- Those who have undergone endoscopic biopsy or puncture biopsy indicating malignant tumors but have not undergone surgery or chemotherapy;
- Previous history of malignant tumor surgery, suspected of recurrence or distant metastasis;
- There is a willingness for puncture biopsy or surgery, and there are no contraindications for puncture biopsy or surgery, and there are no contraindications for anesthesia;
- Sign an informed consent form and undergo a nuclear medicine examination, without any contraindications, with the ability and willingness to participate in the follow-up plan.
Exclusion
- Those who cannot tolerate puncture biopsy or surgical contraindications;
- Those who have undergone radiotherapy and chemotherapy in the past 3 months;
- Individuals who are allergic to multiple drugs or foods;
- Those who refuse nuclear medicine examinations;
- Those who do not agree to sign an informed consent form and are unable or willing to follow up.
Key Trial Info
Start Date :
January 13 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06186427
Start Date
January 13 2024
End Date
December 31 2025
Last Update
January 22 2024
Active Locations (1)
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1
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China, 510080