Status:

COMPLETED

The Impact of Repeated Colonoscopic Insert Method on the Detection Rate of Adenomas in the Sigmoid Colon

Lead Sponsor:

Jianning Yao

Conditions:

Colorectal Polyp

Eligibility:

All Genders

45+ years

Phase:

NA

Brief Summary

Colorectal cancer (CRC) is a malignant tumour originating from the colorectal mucosal epithelium, with rising incidence and mortality rates. Approximately 90% of CRC develops from colorectal polyps, w...

Detailed Description

Colorectal cancer (CRC) is a malignant tumour originating from the colorectal mucosal epithelium, with rising incidence and mortality rates. Currently, CRC ranks third in incidence and second in morta...

Eligibility Criteria

Inclusion

  • Patients who underwent painless colonoscopy at the Gastrointestinal Endoscopy Center of the First Affiliated Hospital of Zhengzhou University and signed the informed consent for the clinical trial;
  • Aged at age 45 and above with BMI \>24.

Exclusion

  • Patients with contraindications to colonoscopy: patients with acute diverticulitis, patients with known or suspected perforation, patients with severe cardiovascular and cerebrovascular lesions, patients with severe hepatic or renal insufficiency, patients with abdominal aneurysm of large arteries, patients with active hemorrhagic descending colonic lesions, patients with acute radiological colorectal inflammation, patients with advanced carcinomas with pelvic metastases or obvious ascites, patients with severe and extensive intestinal adhesions after abdominal or pelvic surgery;
  • Patients with inflammatory bowel disease, colorectal cancer, familial adenomatous polyposis, Peutz-Jeghers syndrome, abdominal wall hernia, patients with a history of colorectal surgery;
  • Patients with incomplete colonoscopy, i.e., those in whom the endoscopist has failed to successfully cannulate the cecum due to technical difficulties;
  • Patients with poor bowel preparation, i.e., patients with a total score of \<6 or any bowel segment of \<2 on the Boston Bowel Preparedness Scale score for poor bowel preparation).

Key Trial Info

Start Date :

January 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 29 2024

Estimated Enrollment :

650 Patients enrolled

Trial Details

Trial ID

NCT06186778

Start Date

January 1 2024

End Date

May 29 2024

Last Update

June 10 2024

Active Locations (1)

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Colonoscopy

Zhengzhou, Henan, China, 450000