Status:

COMPLETED

Dexmedetomidine Versus Fentanyl on Postoperative Analgesic Profile in Laparoscopic Sleeve Gastrectomy

Lead Sponsor:

Helwan University

Conditions:

Pain, Postoperative

Eligibility:

All Genders

20-50 years

Phase:

NA

Brief Summary

Dexmedetomidine (Dex) activates the α2 adrenergic receptor that is present within the locus coeruleus, leading to anxiolysis, hypnosis, analgesia, and sedation. We conducted our research to compare t...

Detailed Description

The participants were assigned to two groups of equal size (32 patients in each group) by the use of computer-generated numbers and sealed opaque envelopes. The participants allocated to the DEX group...

Eligibility Criteria

Inclusion

  • body mass index (BMI) of 35 kg/m2 or more.
  • American Society of Anesthesiology (ASA) physical status of II-III.
  • all participants would have a laparoscopic sleeve gastrectomy (LSG).

Exclusion

  • allergy to α2 -adrenergic agonist.
  • kidney, liver, neuromuscular disorders, and cardiac disease.
  • or patients on opioid medications.

Key Trial Info

Start Date :

July 20 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 20 2023

Estimated Enrollment :

64 Patients enrolled

Trial Details

Trial ID

NCT06186895

Start Date

July 20 2021

End Date

May 20 2023

Last Update

January 2 2024

Active Locations (1)

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Ryad Ghoraba

Tanta, Gharbia Governorate, Egypt, 31527