Status:

ACTIVE_NOT_RECRUITING

Evaluation of Improved Onboard Patient Imaging

Lead Sponsor:

Varian, a Siemens Healthineers Company

Conditions:

Head and Neck Cancer

Breast Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The primary objective of radiation therapy is to deliver a therapeutic dose of radiation precisely to the target while minimizing exposure to healthy surrounding tissues. Image-guided radiation therap...

Eligibility Criteria

Inclusion

  • Patient is willing and able to provide written consent.
  • Patient is at least 18 years of age at the time of consent.
  • Patient has biopsy confirmed malignancy and recommendation for definitive or palliative radiation to the head and neck, breast, lungs, upper GI structures, or pelvis.
  • Patient has ECOG performance status 0-2.
  • Patient will be receiving radiation therapy at University of Maryland Medical Center, Department of Radiation Oncology.

Exclusion

  • Patient is pregnant or attempting pregnancy.
  • Patient has known genetic pre-disposition for sensitivity to radiation (e.g., Li Fraumeni).
  • Patient receives palliative radiation for 5 or fewer fractions.
  • Patient is part of a vulnerable population (per ISO 14155:2020, "individuals who are unable to fully understand all aspects of the investigation that are relevant to the decision to participate, or who could be manipulated or unduly influenced as a result of a compromised position, expectation of benefits or fear of retaliatory response"). This includes prisoners.

Key Trial Info

Start Date :

July 10 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06187103

Start Date

July 10 2024

End Date

December 1 2026

Last Update

December 17 2025

Active Locations (1)

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1

University of Maryland Medical Center

Baltimore, Maryland, United States, 21201-1544