Status:

COMPLETED

Effect of Oral Combined Berberine and Curcumin Pharmacological Therapy on IBS

Lead Sponsor:

Liaquat University of Medical & Health Sciences

Collaborating Sponsors:

University of Liege

Conditions:

Irritable Bowel Syndrome

Eligibility:

All Genders

18+ years

Brief Summary

Irritable bowel syndrome (IBS) is a prevalent, chronic functional gastrointestinal (GI) disorder, characterized by recurrent abdominal discomfort (pain) associated with altered bowel movements. IBS ha...

Detailed Description

Aim of the study: The present clinical study aimed to assess the synergestic therapeutic effect of a combined supplement of standardised extract of BBR and CUR (Enterophytol® PLUS, 200 mg BBR, 49 mg ...

Eligibility Criteria

Inclusion

  • Self-completion of simplified form of the Rome IV IBS diagnostic criteria
  • Had IBS symptoms that appeared before the age of 50
  • Used Enterophytol® PLUS as complementary therapy as two tablets a day for 2-months

Exclusion

  • Those with involuntary weight loss
  • Family history of chronic inflammatory bowel disease, colorectal cancer, celiac disease, rectal discharge, nocturnal symptoms, fever, and abnormalities on clinical examination (abdominal mass, signs of anaemia).

Key Trial Info

Start Date :

August 25 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 15 2023

Estimated Enrollment :

146 Patients enrolled

Trial Details

Trial ID

NCT06187298

Start Date

August 25 2020

End Date

December 15 2023

Last Update

January 29 2024

Active Locations (1)

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Liaquat University of Medical and Health Sciences

Jāmshoro, Pakistan