Status:
COMPLETED
UR+AIMS Gout Wearable Skin Uric Acid Monitor Study
Lead Sponsor:
University of California, Los Angeles
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Gout
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
15 patients with gout \[10 patients no recent urate-lowering therapy (ULT) and 5 patients on stable urate-lowering therapy (ULT)\] will be invited to participate in a standardized meal at the UCLA Hum...
Detailed Description
First Visit at the UCLA Human Nutrition Center: * Patients will sign the informed consent, then answer some study questionnaires. * The Uric Acid and Metabolite Monitor System (UR+AIMS) skin patch an...
Eligibility Criteria
Inclusion
- Age \> 18 with diagnosis of gout (screening positive ACR/EULAR Gout Classification Criteria - see screening survey) and eGFR \> 60 (within the last 12-months).
- For the 10 patients with gout off urate-lowering therapy (ULT) \[no Allopurinol, febuxostat, or probenecid prescription within the last 6-months\] and serum urate (SU) \> 7 mg/dL (within the last 12-months).
- For the 5 patients with gout on urate-lowering therapy (ULT) \[no dose change within the last 30 days\].
Exclusion
- Contraindications to miosis, which include acute iritis, narrow-angle glaucoma
- Known Hypersensitivity to pilocarpine hydrochloride
- Pupillary block glaucoma (ophthalmic solution)
- Subjects reporting any allergy to glue or latex or any allergy to food that will be provided in the study (sardines in extra virgin olive oil and Sprite).
Key Trial Info
Start Date :
March 10 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 3 2025
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT06187519
Start Date
March 10 2025
End Date
September 3 2025
Last Update
November 24 2025
Active Locations (1)
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1
UCLA
Los Angeles, California, United States, 90095