Status:

UNKNOWN

Effect of Perioperative Oral Pregabalin in Total Knee Replacement

Lead Sponsor:

Bahrain Defence Force Hospital

Conditions:

Postoperative Pain

Eligibility:

All Genders

18-85 years

Phase:

PHASE4

Brief Summary

This interventional randomized control trial aim to determine efficacy and safety of Oral pregabalin in improving after surgery pain control in patients undergoing total knee replacement surgeries und...

Detailed Description

After obtaining approval from the institutional ethical committee and informed written consent, 120 patients fulfilling the inclusion criteria will be included in this study. The patients will be rand...

Eligibility Criteria

Inclusion

  • Age between 18 to 85 year
  • Elective Regional anesthesia.
  • Able to follow study protocol

Exclusion

  • ASA -IV
  • Age \<18 \& \> 85 years
  • Patients on pregabalin for chronic neuropathic pain.
  • Patient under General anesthesia
  • Patients with chronic liver failure
  • Patients with chronic renal failure on Hemodialysis
  • Patients on opioid (\>3 month)
  • Patient with complicated knee surgery

Key Trial Info

Start Date :

September 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 30 2025

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT06187922

Start Date

September 1 2023

End Date

July 30 2025

Last Update

January 3 2024

Active Locations (1)

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Bahrain Defence Force

Manama, Bahrain, 323